Dezawa MuseCells®
The source. A defined, SSEA-3-positive, stress-enduring cell population — the origin of everything downstream. Not a broad, pooled MSC mix, but a selected, authenticated starting point.
A professional, clinical-grade system for skin and scalp — the characterized signaling layer, released by stress-enduring Dezawa MuseCells® and prepared at the moment of care.
Every Dezawa signaling product begins with the Authentic Dezawa MuseCell® — signaling, two ways: the complete secretome, and the characterized exosome layer within it.
The source. A defined, SSEA-3-positive, stress-enduring cell population — the origin of everything downstream. Not a broad, pooled MSC mix, but a selected, authenticated starting point.
The complete profile. The full complement of factors these cells secrete — growth factors, cytokines, regulatory RNA and extracellular vesicles — characterized as a whole.
The precision layer. The exosome fraction of that secretome — nanosized extracellular vesicles, independently characterized and prepared, lyophilized, for professional use.
A cell's secretome is the complete set of factors it releases. The exosome is one characterized layer within it — the vesicular fraction. Here is how the two relate in the Dezawa platform.
Nanosized extracellular vesicles carrying proteins, regulatory RNA and lipids — measurable, marker-positive and size-appropriate in independent analyses.
The vesicular layer plus the soluble factors an exosome-only preparation leaves behind — the fuller complement, from one defined source.
Growth factors · Cytokines · Regulatory RNA · Extracellular vesicles
In a published proteomic comparison, the DMC secretome was measurably distinct from standard bone-marrow and adipose MSC secretomes — a different signal, from a different source.
Proteomic comparison of the Muse-cell secretome vs bone-marrow and adipose MSC secretomes — factors associated with stemness, apoptosis regulation and immunomodulation. Alessio N, et al. Cell Cycle 2017;16(1):33–44. PMID 27463232 · full text.
Because a signal is only as trustworthy as the cell it comes from, Dezawa Muse Signaling™ products begin with a defined, SSEA-3-positive source. Dezawa MuseExosomes® are developed from authenticated MuseCell® cultures and supported by analytical characterization: a measurable EV layer, marker-positive, size-appropriate, sterile in tested vials, and morphologically intact in independent analyses.
Supports luminosity and an even, refreshed-looking surface following professional application.
Paired with injectable-grade hyaluronic acid to support hydration and a plumper-looking skin barrier.
Designed to support texture, tone and overall skin quality within advanced aesthetic protocols.
Supports firmer, more resilient-looking skin as part of a physician-led treatment plan.
Muse exosomes are extracellular vesicles released by Dezawa MuseCells® — a defined, stress-enduring cell source. In professional skincare they are used to support overall skin appearance, including hydration, texture and tone.
The secretome is the complete set of factors a cell secretes; the exosome is one characterized layer within it — the vesicular fraction. Dezawa MuseExosomes® are that characterized layer; the Muse Secretome® is the whole profile.
Most aesthetic exosome products are derived from broad MSC populations, such as adipose or umbilical-cord MSCs. Dezawa MuseExosomes® begin from a more defined biological source — SSEA-3-positive, stress-enduring Dezawa MuseCells® — and are supported by independent characterization of the vesicle layer.
They are supplied in a lyophilized format for professional use, reconstituted with the hyaluronic acid diluent at the point of care, and applied within physician-led aesthetic protocols — including alongside professional procedures such as microneedling. For professional use only.
Every citation links to the source. Product-characterization statements describe analytical testing of the tested preparation; they are not efficacy claims.
For US customers and professional use only. These products have not been evaluated or approved by the United States Food and Drug Administration (FDA) and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. Any clinical use is at the sole discretion of a licensed healthcare provider and must comply with all applicable federal and state laws and regulations. Individual results may vary. No claims are made regarding safety or effectiveness for any specific clinical application.
MuseCell Innovations® PTE Ltd. (MCI) is an intellectual-property licensing company specializing in Dezawa MuseCells® and Dezawa MuseExosomes® technologies. MCI does not sell or distribute products. Dezawa MuseExosomes® are a professional product of Dezawa Aesthetics™, available to licensed practitioners through authorized order portals.
Explore the professional product at Dezawa Aesthetics™, or the underlying cell science at MuseCell Innovations®.