I. In the bloodstream
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Authentic muse stem cells — Dezawa MuseCells® from MuseCell Innovations®, the global IP owner

Pluripotent-like · IV-deliverable

Most stem cells
never
reach
the injury.

Dezawa MuseCells® do.

Damaged tissue · S1P signal

Injury releases
a distress signal.

Dezawa MuseCells® read it through the S1PR2 receptor — and vector to the source.

Homing · whole-body repair

Delivered systemically.
Targeted precisely.

Cleared debris. Replaced cells. Repair and recovery reported in published studies — heart, brain, liver, and beyond. Noda 2020 · Niizuma 2023 · Shono 2021

MuseCell Innovations
Regenerating life at its source

Discovered at Tohoku University in 2010, with a deep peer-reviewed evidence base. These are the only Muse cells the literature recognizes.

The evidence base

0+

peer-reviewed publications on Dezawa MuseCells®. One of the deepest evidence bases in regenerative medicine.

Published in PNASNature ProtocolsScientific ReportsCirculation ResearchStem Cells Translational MedicineFrontiers in Bioengineering & BiotechnologyJ Invest Dermatol
Dezawa MuseCells®

Naturally occurring. Pluripotent-like. IV-deliverable.

SSEA-3⁺ surface marker. Immune-privileged. Non-tumorigenic. Discovered 2010, Tohoku University.

Pluripotent-like cells delivered by IV — no immunosuppression required.

Most stem cells never reach the injury. These do. They circulate to the source of damage and stay long enough to repair it.

Read the Authentic Dezawa MuseCells® whitepaper →
One method · One ecosystem

The Dezawa Standard.

The Dezawa Standard

Heritage, method, verification.

A discovery at Tohoku University, the licensed method that carries its discoverer's name, and a Certificate of Analysis behind every vial.

01

Heritage

A 2010 discovery at Tohoku University by Dr. Mari Dezawa — and the patented manufacturing method that carries her name.

02

Method

The Dezawa Method™ — a licensed, IP-protected manufacturing protocol. SSEA-3⁺ verification. Validated potency, purity, and clinical reproducibility.

03

Verification

Dezawa-Verified™ — every vial carries a Certificate of Analysis from an MCI-authorized laboratory. Lot-traced with verified chain-of-custody.

Tohoku, 2010.

From a Tohoku notebook — to one of the most robust evidence bases in regenerative medicine.

2010
PNAS
Discovery

Dr. Mari Dezawa identifies pluripotent-like cells in connective tissue. The body's own repair cells — named, isolated, characterized.

Kuroda Y, Wakao S, Dezawa M. PNAS, 2010.
2013
Nature Protocols
The Method

The foundational Muse-cell research enters the peer-reviewed literature — the science The Dezawa Method™ would later build on.

Kuroda Y et al. Nature Protocols, 2013.
2018
Multi-organ
Reach

Independent labs study Muse cells across the heart, brain, liver, and kidney — the mechanism holds across organ systems.

Multiple independent publications, 2014–2020.
2025
Evidence base
The Standard

A deep, growing peer-reviewed evidence base. Commercial production, distributed exclusively through MCI-authorized partners under The Dezawa Method™.

Dezawa M. Frontiers in Bioengineering & Biotechnology, 2025.
Delivered systemically · Targeted precisely

How a cell finds where it's needed.

By IV. Past the lung. Toward the injury.

Diagram of how a Dezawa MuseCell finds where it's needed. The cell enters the bloodstream at the top, the body emits an S1P distress signal to the left, the cell homes via the S1PR2 receptor to the right, and the two paths converge at the site of injury at the bottom for repair.
Phase 01 · Bloodstream

The cell enters circulation.

Dezawa MuseCells® travel ready to respond anywhere in the body.

Phase 02 · Signal

The body calls.

Damaged tissue releases S1P — the cell is tuned to detect it.

Phase 03 · Homing

The cell answers.

S1PR2 guides the cell directly to the injury, past the lung trap.

Phase 04 · Repair

The injury heals.

Debris cleared, tissue repaired — regeneration and recovery in published models Wakao 2022 · Uchida 2017.

One mechanism · one platform

One conserved mechanism.

The body's repair protocol.

01 / 06
Foundational research

Neurology & Brain Health.

StrokeTraumatic brain injuryCerebral ischemiaSpinal cord injury
studies & supporting publications · 2010–2025
Sato Y et al. Safety and tolerability of a Muse cell-based product in neonatal hypoxic-ischemic encephalopathy with therapeutic hypothermia (SHIELD trial). Stem Cells Translational Medicine, 2024.
02 / 06
Longevity

Longevity & age-related degeneration — early-stage research.

Cellular senescenceVascular agingFrailty markers
Healthspan optimization research
Dezawa M. Comparison of MSCs and Muse cells: the possible use for healthspan optimization. Biogerontology, 2025.
03 / 06
Orthopedics

Orthopedics & chronic pain.

Cartilage defectsOsteoarthritisJoint recoveryMusculoskeletal repair
New studies in preparation · trials advancing
Koda M et al. Safety and feasibility of intravenous administration of a single dose of allogenic-Muse cells to treat human cervical traumatic spinal cord injury: a clinical trial. Stem Cell Research & Therapy, 2024.
04 / 06
Sister brand

Performance & recovery.

Muscle repairmTBI in service membersAccelerated return-to-dutySports recovery
DHP
A Dezawa sister brand
Pursued under Dezawa High Performance™. Partnership: Axis BioVentures · Special Operations Forces networks.
05 / 06
Cardiac & Vascular

Cardiac & vascular repair.

Post-MI tissue protectionAngiogenesisIschemia-reperfusionVascular endothelial repair
Published cardiac & vascular research
Noda T, Nishigaki K, Minatoguchi S. Safety and Efficacy of Human Muse Cell-Based Product for Acute Myocardial Infarction in a First-in-Human Trial. Circulation Journal, 2020.
06 / 06
Sister brand

Aesthetics & skin health.

Dezawa MuseExosomes®Skin regenerationPhysician-led skincareCosmetic dermatology
DMA
A Dezawa sister brand
Shelf-stable exosome formulation. No cold-chain required. Available at dezawaaesthetics.com.

Many systems, one Dezawa MuseCell®.

As referenced in
Built by the people who define the field

The architects of The Dezawa Standard.

From the lab in Tohoku to the Scientific Advisory Board, the Management Team, and the Aesthetics and Military advisory networks behind the brand.

Professor

Mari DezawaMD, PhD

出沢真理

World leader in stem-cell research & regenerative medicine

Chair, MCI Science Advisory Board · Discoverer of Muse cells, 2010

Read full biography →
United States
Peter H. DiamandisMD
Strategic Advisor
Co-founder, Singularity University · Founder, Abundance360 · New York Times bestselling author.
United States
William G. Austen, Jr.MD
Plastic & Reconstructive Surgery · Burn Surgery
Chief of Plastic and Reconstructive Surgery and Burn Surgery at Massachusetts General Hospital and the Sumner M. Redstone Professor of Surgery at Harvard Medical School
United States
Neal ElAttracheMD
Orthopedic Surgeon · Sports Medicine
Cedars-Sinai Kerlan-Jobe · Head Team Physician, LA Dodgers & Rams.
United States
Rowan PaulMD
Regenerative Sports Medicine
Professor Dartmouth Geisel SofM, Launch Regenerative, SF Ballet, SF, CA
United States
Joseph PuritaMD
Regenerative Medicine Expert
Inaugural president, American Academy & Board of Regenerative Medicine.
United States
Christopher DodsonMD
Head of Orthopaedics, Vincera Institute
Sports medicine surgeon · Philadelphia 76ers (former) · NHL consultant.
United States
Kathleen O'NeilMD · FAARM
Regenerative Medicine Expert
Founder & Medical Director of Treat Wellness, Boston.
United States
Johannes RoedlMD · PhD
Interventional MSK Radiologist
Thomas Jefferson University · Philadelphia Eagles team physician.
United States
Ethan KellumMD
Regenerative Orthopedics Specialist
Team physician · Tennessee Titans · USA Basketball.
United Kingdom
Ansar MahmoodMB ChB · FRCS
Orthopedic Trauma · Regenerative Medicine
UK · founder, Academy of Regenerative Medicine.
United States
Jonathan L. GlashowMD
Orthopedic Surgeon · Sports Medicine
NYU Grossman School of Medicine · four decades, NYC.
United States
Ian WhitePhD
Biological Production Expert
CEO & CSO of Neobiosis · CSO for Ways2Well.
United States
Vijay VadMD
Sports Medicine, HSS · Asst. Prof, Weill Cornell
Author of Back Rx · founder of the Vad Foundation.
United States
Harry AdelsonND
Regenerative Medicine Expert
Founder, Docere Clinics · 10,000+ stem cell procedures.
United States
Matt CookMD · FAARM
Founder & CMO, BioReset Medical
20+ years in regenerative medicine.
Canada
Ted HoydaMD · PhD · FRCSC
Regenerative Urologist & Neuroscientist
University of British Columbia trained.
United States
Jonathann KuoMD
Longevity Medicine Specialist
Founder & CEO, Extension Health · NYC + Miami.
Mexico
J. Omar Novelo-BaezaMD
Regenerative Medicine Specialist
Medical Director, Neorgana Regenerative · pediatric neuroregen.
United Arab Emirates
Sammy I. MasriMD
Sports, Regenerative & Longevity Medicine
Founder & CEO, Lifespan Clinic, Dubai · 20+ years in clinical practice.
United States
Deepti AgarwalMD
Precision Medicine
Triple board-certified · Northwestern · Weill Cornell trained.
United States
William G. Austen, Jr.MD
Plastic & Reconstructive Surgery · Burn Surgery
Chief of Plastic and Reconstructive Surgery and Burn Surgery at Massachusetts General Hospital and the Sumner M. Redstone Professor of Surgery at Harvard Medical School
Colombia
Alfredo HoyosMD
Plastic Surgeon · Body Contouring
Pioneer of High Definition Liposculpture · founder, Total Definer.
United States
Ryan NeinsteinMD
Strategic Advisor, Advanced Aesthetic Medicine
Founder, Neinstein Plastic Surgery · New York City.
United States
John LaykeDO
Plastic Surgeon · Regenerative Medicine
Co-founder, Beverly Hills Plastic Surgery Group.
United States
Steven R. CohenMD · FACS
Founder & CEO, FACES+ Plastic Surgery
Clinical Professor, UC San Diego School of Medicine · Section Editor, Aesthetic Surgery Journal.
United States
Rob Lively 
Chair, Military Advisory Board
Retired U.S. Army Command Sergeant Major · 28 years USASOC.
United States
Kenneth M. FordPhD
Founder & CEO Emeritus, IHMC
AAAI Fellow · charter NAI Fellow · former NASA Advisory Chairman.
United States
Alex R. Oliver 
Military Advisory Board
Retired Navy SEAL · Naval Special Warfare Development Group.
United Kingdom
Ed SandersCGC
Military Advisory Board
AUKUS Programme at Rolls-Royce · 22nd British SAS · 1st NZ SAS.
Canada
Sebastien Bouchard 
Operator
Former Canadian Special Operations Forces · founding CSOR.
United States
Daniel David Corbett III 
Operator
Former U.S. Navy SEAL · SEAL Teams 5, 6, and 17 · author American Mercenary.
United States
Mark W. Erwin 
Co-Chair, Military Advisory Board
Co-Chair, MCI Military Advisory Board.
Austria
Dominik DuscherMD · PhD
President & CEO
Vienna · UCL · Harvard · Stanford trained · 160+ publications.
United States
Jeffrey J. WiegersMD
Chief Medical Officer
Double board-certified anesthesiology · interventional pain.
United Kingdom
Mike HewisonFCCA
Chief Financial Officer
30+ years in regulated financial services.
United States
Kaitlin M. CarrollMPH · PhD
COO & Head of Compliance
15+ years across academic medicine and industry.
Canada
Kevin SerrePhD
EVP Business Development · CEO, DHP
President of MCI · former Human Performance Lead, CANSOFCOM.
United States
Lonnie Rae Kurlander 
EVP, Brand
Founder of Medal (acquired by Ciox) · Vanderbilt MCB.
United States
Dana Deutsch 
Vice President, Digital Media & Marketing
Leads brand, content & social at MuseCell Innovations.
United States
Ashley FrancisBSN, RN
Vice President, Strategic Partnerships
BSN, RN · 20+ years critical care · Mass General, Cedars-Sinai, Keck USC.
Canada
James McRoberts 
Chairman
Founder of MuseCell Innovations · former Executive Chairman, Paysafe Group (NYSE: PSFE).
Watch the film · 2:09

What if the body already knew how to repair itself.

MCI Hero Film poster
2:09
The Difference

How Dezawa MuseCells® differ from traditional MSCs.

Four attributes that separate Dezawa MuseCells® from conventional mesenchymal stem cells — drawn from 120+ peer-reviewed publications.

 Dezawa MuseCells®Traditional MSCs
Differentiation potentialAll three germ layers (ecto-/meso-/endoderm)Osteocytes, chondrocytes, adipocytes
Immune rejection (donor cells)None~15%
Distribution after IV injectionTarget (damaged) organLungs (first-pass)
Delivery rate to target organ (IV)~15%Less than 1%, if any
For licensed physicians

Authorized distributors. Authentic Dezawa MuseCells®.

Every vial is Dezawa-Verified™ — lot-traced, COA-accompanied, and produced under The Dezawa Method™. In the United States, available through Regen Processing and Axis Therapeutics.

Not in the US? See all distributors →

For patients

Authorized. Authentic.

Authentic Dezawa MuseCells® are administered only in MCI-authorized clinics.

FL

Prime Longevity

Miami Beach

FL

OneLife Health and Performance

Palm Beach Gardens

FL

Stems Regenerative Medicine

Miami Beach

FL

Pur-Form Health

Boca Raton

US

Extension Health

extension.health

TN

Dr. Ethan Kellum

Franklin

UT

Docere Clinic

Park City

TX

Marcella Madera, MD

Fort Worth

TX

NeuroSolution Center of Austin

Cedar Park

TX

Ways2Well

Austin

FL

Prime Longevity

Miami Beach

FL

OneLife Health and Performance

Palm Beach Gardens

FL

Stems Regenerative Medicine

Miami Beach

FL

Pur-Form Health

Boca Raton

US

Extension Health

extension.health

TN

Dr. Ethan Kellum

Franklin

UT

Docere Clinic

Park City

TX

Marcella Madera, MD

Fort Worth

TX

NeuroSolution Center of Austin

Cedar Park

TX

Ways2Well

Austin

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